Phenotypes associated with this allele

• Allele Symbol: 9030622O22Rik⁺
• Allele Name: wild type
• Allele ID: MGI:5481621
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	9030622O22Rik^em1Eem/9030622O22Rik^+ Foxa2^tm1.1Khk/Foxa2^+	involves: 129P2/OlaHsd * C57BL/6 * CD-1	MGI:6393316

Genotype
MGI:6393316

cx1

• Allelic Composition: 9030622O22Rik^em1Eem/9030622O22Rik⁺; Foxa2^tm1.1Khk/Foxa2⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

respiratory system inflammation ( J:284174 )

• by 8-12 weeks of age, mice exhibit areas of peribronchial and perivascular inflammation, consisting predominantly of B220+ B cells

• inflammation is most notable in the subepithelial region of airway branch points

• CD3e+ T cells are found interspersed among the B cells at foci of inflammation

respiratory system

respiratory system inflammation ( J:284174 )

• by 8-12 weeks of age, mice exhibit areas of peribronchial and perivascular inflammation, consisting predominantly of B220+ B cells

• inflammation is most notable in the subepithelial region of airway branch points

• CD3e+ T cells are found interspersed among the B cells at foci of inflammation

abnormal respiratory mucosa goblet cell morphology ( J:284174 )

• goblet cell metaplasia, with greater numbers of goblet cells than in single Foxa2 heterozygotes