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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhbgtm1.1Idw
targeted mutation 1, I David Weiner
MGI:5477809
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Rhbgtm1.1Idw/Rhbgtm1.1Idw
Tg(ATP6V1B1-cre)45Rnel/0 		involves: C57BL/6 MGI:5477810


Genotype
MGI:5477810
cn1
Allelic
Composition		 Rhbgtm1.1Idw/Rhbgtm1.1Idw
Tg(ATP6V1B1-cre)45Rnel/0
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhbgtm1.1Idw mutation (1 available); any Rhbg mutation (22 available)
Tg(ATP6V1B1-cre)45Rnel mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:195261 )
N
• no differences in titratable acid excretion, urine pH, urinary electrolyte excretion, serum bicarbonate levels, or serum potassium levels are detected under basal or acid loading conditions
decreased urine ammonia level ( J:195261 )
• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls
• however, basal ammonia excretion is similar to controls

renal/urinary system
decreased urine ammonia level ( J:195261 )
• following acid loading, urinary ammonia levels are reduced by about 25% compared to controls
• however, basal ammonia excretion is similar to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory