All Phenotypes Plxnd1<b2b1863Clo> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Plxnd1^b2b1863Clo
Bench to Bassinet Program (B2B/CVDC), mutation 1863 Cecilia Lo
MGI:5476170

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo	C57BL/6J-Plxnd1^b2b1863Clo	MGI:5476432

Allelic Composition	Plxnd1^b2b1863Clo/Plxnd1^b2b1863Clo
Genetic Background	C57BL/6J-Plxnd1^b2b1863Clo

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Plxnd1^b2b1863Clo mutation (1 available); any Plxnd1 mutation (86 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Mutant 1863-002-4 (E16.5) has a hypoplastic transverse arch and malaligned great arteries

cardiovascular system

right aortic arch ( J:175213 )

dual inferior vena cava ( J:175213 )

persistent truncus arteriosus type ii ( J:175213 )

• truncus arteriosus type IIa

double outlet right ventricle ( J:175213 )

atrioventricular septal defect ( J:175213 )

craniofacial

cleft palate ( J:175213 )

digestive/alimentary system

cleft palate ( J:175213 )

hematopoietic system

thymus hypoplasia ( J:175213 )

immune system

thymus hypoplasia ( J:175213 )

renal/urinary system

absent kidney ( J:175213 )

endocrine/exocrine glands

thymus hypoplasia ( J:175213 )

growth/size/body

cleft palate ( J:175213 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
DiGeorge syndrome		DOID:11198	OMIM:188400	J:175213

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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