Phenotypes associated with this allele

• Allele Symbol: Adar^{tm1b(EUCOMM)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5474756
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adar^tm1b(EUCOMM)Wtsi/Adar^tm1b(EUCOMM)Wtsi	B6N(Cg)-Adar^tm1b(EUCOMM)Wtsi/J	MGI:5763826
ht2	Adar^tm1b(EUCOMM)Wtsi/Adar^+	B6N(Cg)-Adar^tm1b(EUCOMM)Wtsi/J	MGI:5763825

Genotype
MGI:5763826

hm1

• Allelic Composition: Adar^{tm1b(EUCOMM)Wtsi}/Adar^{tm1b(EUCOMM)Wtsi}
• Genetic Background: B6N(Cg)-Adar^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0087_1_D11

Data Sources

IMPC Data for Adar

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal embryo size ( J:211773 )

IMPC - JAX

abnormal neural tube closure ( J:211773 )

IMPC - JAX

abnormal placenta size ( J:211773 )

IMPC - JAX

pale yolk sac ( J:211773 )

IMPC - JAX

growth/size/body

abnormal embryo size ( J:211773 )

IMPC - JAX

integument

pallor ( J:211773 )

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

nervous system

abnormal neural tube closure ( J:211773 )

IMPC - JAX

Genotype
MGI:5763825

ht2

• Allelic Composition: Adar^{tm1b(EUCOMM)Wtsi}/Adar⁺
• Genetic Background: B6N(Cg)-Adar^{tm1b(EUCOMM)Wtsi}/J
• Cell Lines: EPD0087_1_D11

Data Sources

IMPC Data for Adar

homeostasis/metabolism

decreased circulating glucose level ( J:211773 )

♂

IMPC - JAX