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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ralgapa2tm1Hhor
targeted mutation 1, H Horiuchi
MGI:5469375
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ralgapa2tm1Hhor/Ralgapa2tm1Hhor C57BL/6J-Ralgapa2tm1Hhor MGI:5469376


Genotype
MGI:5469376
hm1
Allelic
Composition		 Ralgapa2tm1Hhor/Ralgapa2tm1Hhor
Genetic
Background		 C57BL/6J-Ralgapa2tm1Hhor
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ralgapa2tm1Hhor mutation (0 available); any Ralgapa2 mutation (118 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased incidence of tumors by chemical induction ( J:193368 )
• all N-butyl-N-(4-hydroxybutyl) nitrosamine-treated develop invasive urothelial bladder tumors unlike wild-type mice
increased urinary system tumor incidence ( J:193368 )
• all N-butyl-N-(4-hydroxybutyl) nitrosamine-treated develop invasive urothelial bladder tumors unlike wild-type mice

homeostasis/metabolism
increased incidence of tumors by chemical induction ( J:193368 )
• all N-butyl-N-(4-hydroxybutyl) nitrosamine-treated develop invasive urothelial bladder tumors unlike wild-type mice

renal/urinary system
increased urinary system tumor incidence ( J:193368 )
• all N-butyl-N-(4-hydroxybutyl) nitrosamine-treated develop invasive urothelial bladder tumors unlike wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory