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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arhgef15tm1Nmoc
targeted mutation 1, Naoki Mochizuki
MGI:5464934
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Arhgef15tm1Nmoc/Arhgef15tm1Nmoc B6.Cg-Arhgef15tm1Nmoc MGI:5464991


Genotype
MGI:5464991
hm1
Allelic
Composition		 Arhgef15tm1Nmoc/Arhgef15tm1Nmoc
Genetic
Background		 B6.Cg-Arhgef15tm1Nmoc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgef15tm1Nmoc mutation (0 available); any Arhgef15 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Retardation of retinal vascular growth in Arhgef15tm1Nmoc/Arhgef15tm1Nmoc mice

cardiovascular system
abnormal retina vasculature morphology ( J:191977 )
• retinal vasculature extension is retarded at P5 and P8 reducing the total vessel area compared with wild-type mice
• however, mice exhibit normal vessel density and branch points

vision/eye
abnormal retina vasculature morphology ( J:191977 )
• retinal vasculature extension is retarded at P5 and P8 reducing the total vessel area compared with wild-type mice
• however, mice exhibit normal vessel density and branch points




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory