Phenotypes associated with this allele

• Allele Symbol: Msx1^{tm1b(KOMP)Wtsi}
• Allele Name: targeted mutation 1b, Wellcome Trust Sanger Institute
• Allele ID: MGI:5463966
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Msx1^tm1b(KOMP)Wtsi/Msx1^tm1b(KOMP)Wtsi	C57BL/6N-Msx1^tm1b(KOMP)Wtsi/J	MGI:5631321
ht2	Msx1^tm1b(KOMP)Wtsi/Msx1^+	C57BL/6N-Msx1^tm1b(KOMP)Wtsi/J	MGI:5759340

Genotype
MGI:5631321

hm1

• Allelic Composition: Msx1^{tm1b(KOMP)Wtsi}/Msx1^{tm1b(KOMP)Wtsi}
• Genetic Background: C57BL/6N-Msx1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0334_7_D05

Data Sources

IMPC Data for Msx1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

digestive/alimentary system

cleft palate ( J:211773 )

IMPC - JAX

growth/size/body

abnormal facial morphology ( J:211773 )

IMPC - JAX

cleft palate ( J:211773 )

IMPC - JAX

homeostasis/metabolism

cyanosis ( J:211773 )

♂

IMPC - JAX

mortality/aging

preweaning lethality, complete penetrance ( J:211773 )

IMPC - JAX

Genotype
MGI:5759340

ht2

• Allelic Composition: Msx1^{tm1b(KOMP)Wtsi}/Msx1⁺
• Genetic Background: C57BL/6N-Msx1^{tm1b(KOMP)Wtsi}/J
• Cell Lines: EPD0334_7_D05

Data Sources

IMPC Data for Msx1

behavior/neurological

decreased thigmotaxis ( J:211773 )

♂

IMPC - JAX

cardiovascular system

increased heart weight ( J:211773 )

♂

IMPC - JAX

growth/size/body

increased heart weight ( J:211773 )

♂

IMPC - JAX

homeostasis/metabolism

increased circulating free fatty acids level ( J:211773 )

♂

IMPC - JAX