All Phenotypes Tg(Rp1)T1Eap MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Rp1)T1Eap
transgene insertion T1, Eric A Pierce
MGI:5463932

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Rp1^tm2.1Eap/Rp1^tm2.1Eap Tg(Rp1)T1Eap/0	involves: 129S7/SvEvBrd * C57BL/6	MGI:5463941
tg2	Tg(Rp1)T1Eap/0	involves: C57BL/6	MGI:5463943

Allelic Composition	Rp1^tm2.1Eap/Rp1^tm2.1Eap Tg(Rp1)T1Eap/0
Genetic Background	involves: 129S7/SvEvBrd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rp1^tm2.1Eap mutation (0 available); any Rp1 mutation (121 available)
Tg(Rp1)T1Eap mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:191685 )

N	• normal retinal structures preserved at 2 and 12 months of age • outer segments largely preserved • improved ERG

abnormal cone electrophysiology ( J:191685 )

• cone b-waves at 90% normal at 12 months

abnormal rod electrophysiology ( J:191685 )

• rod a-wave at 57% normal at 12 months

• rod b-wave at 71% normal at 12 months

Allelic Composition	Tg(Rp1)T1Eap/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

vision/eye phenotype ( J:191685 )

N	• histology of photoreceptors well preserved to 1 year of age • normal retinal function by ERG to 1 year of age

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