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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Optctm1.1Pnb
targeted mutation 1.1, Paul N Bishop
MGI:5462239
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Optctm1.1Pnb/Optctm1.1Pnb involves: 129S7/SvEvBrd * C57BL/6 MGI:5462243


Genotype
MGI:5462243
hm1
Allelic
Composition		 Optctm1.1Pnb/Optctm1.1Pnb
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Optctm1.1Pnb mutation (0 available); any Optc mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal induced retina neovascularization ( J:191528 )
• in an oxygen-induced retinopathy model, mice exhibit more preretinal neovascularization compared with wild-type mice

vision/eye
abnormal induced retina neovascularization ( J:191528 )
• in an oxygen-induced retinopathy model, mice exhibit more preretinal neovascularization compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory