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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tada3tm1.1Viba
targeted mutation 1.1, Vimla Band
MGI:5462193
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tada3tm1.1Viba/Tada3tm1.1Viba involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:5462196
cn2
 		Tada3tm1.1Viba/Tada3tm1.1Viba involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:5462197


Genotype
MGI:5462196
hm1
Allelic
Composition		 Tada3tm1.1Viba/Tada3tm1.1Viba
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tada3tm1.1Viba mutation (0 available); any Tada3 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:190249 )
• mice are viable and fertile and exhibit no gross abnormalities




Genotype
MGI:5462197
cn2
Allelic
Composition		 Tada3tm1.1Viba/Tada3tm1.1Viba
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tada3tm1.1Viba mutation (0 available); any Tada3 mutation (31 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal mitosis ( J:190249 )
• mouse embryonic fibroblasts infected with a cre-expressing adenovirus exhibit delay in G1 to S and G2/M to G1 progression compared with wild-type cells
decreased fibroblast proliferation ( J:190249 )
• in mouse embryonic fibroblasts infected with a cre-expressing adenovirus
• however, proliferation is rescued by over-expression of the human cDNA or knock-down of Cdkn1b




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory