Phenotypes associated with this allele

• Allele Symbol: Ap3b2^m2J
• Allele Name: mutation 2 Jackson
• Allele ID: MGI:5449877
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ap3b2^m2J/Ap3b2^m2J	B6;129S-Ap3b2^m2J/GrsrJ	MGI:5547588

Genotype
MGI:5547588

hm1

• Allelic Composition: Ap3b2^m2J/Ap3b2^m2J
• Genetic Background: B6;129S-Ap3b2^m2J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

tonic-clonic seizures ( J:205908 , J:222308 )

• onset is by eight to ten weeks of age (J:205908)

nervous system

tonic-clonic seizures ( J:205908 , J:222308 )

• onset is by eight to ten weeks of age (J:205908)

hearing/vestibular/ear

increased or absent threshold for auditory brainstem response ( J:205908 )

• ABR assessment of hearing on two homozygotes at approximately three months of age showed normal hearing at all frequencies except for a slightly elevated threshold at 32kHz

vision/eye

vision/eye phenotype ( J:205908 )

N • electroretinography of one homozygote at eleven weeks of age was normal, and ophthalmoscopic examination of three homozygotes at eleven weeks of age found no abnormalities