All Phenotypes Kdm6a<tm2.1Kaig> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kdm6a^tm2.1Kaig
targeted mutation 2.1, Kai Ge
MGI:5448826

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig	involves: 129 * C57BL/6	MGI:5779972
ot2	Kdm6a^tm2.1Kaig/Y	involves: 129 * C57BL/6	MGI:5779971

Allelic Composition	Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6a^tm2.1Kaig mutation (0 available); any Kdm6a mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

muscle phenotype ( J:232700 )

N	• mice exhibit normal myofiber integrity

abnormal muscle precursor cell morphology ( J:232700 )

• muscle progenitor cells fail to differentiate ex vitro

impaired skeletal muscle regeneration ( J:232700 )

• following CTX-induced muscle injury

Allelic Composition	Kdm6a^tm2.1Kaig/Y
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kdm6a^tm2.1Kaig mutation (0 available); any Kdm6a mutation (37 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

muscle phenotype ( J:232700 )

N	• mice exhibit normal myofiber integrity

abnormal muscle precursor cell morphology ( J:232700 )

• muscle progenitor cells fail to differentiate ex vitro

impaired skeletal muscle regeneration ( J:232700 )

• following CTX-induced muscle injury

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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