About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mdm2tm3.1Snj
targeted mutation 3.1, Steven N Jones
MGI:5446922
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mdm2tm3.1Snj/Mdm2tm3.1Snj involves: 129S4/SvJae * C57BL/6 MGI:5446929


Genotype
MGI:5446929
hm1
Allelic
Composition		 Mdm2tm3.1Snj/Mdm2tm3.1Snj
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mdm2tm3.1Snj mutation (0 available); any Mdm2 mutation (54 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased salivary gland tumor incidence ( J:189297 )
• in 24 months, 1 in 24 mice develops salivary gland epithelium

digestive/alimentary system
increased salivary gland tumor incidence ( J:189297 )
• in 24 months, 1 in 24 mice develops salivary gland epithelium

cellular
cellular phenotype ( J:189297 )
N
• irradiated thymocytes exhibit normal apoptosis
• untreated and irradiated mouse embryonic fibroblasts exhibit normal proliferation

endocrine/exocrine glands
increased salivary gland tumor incidence ( J:189297 )
• in 24 months, 1 in 24 mice develops salivary gland epithelium

immune system
immune system phenotype ( J:189297 )
N
• irradiated thymocytes exhibit normal apoptosis




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory