Phenotypes associated with this allele

• Allele Symbol: Mdm2^tm3.1Snj
• Allele Name: targeted mutation 3.1, Steven N Jones
• Allele ID: MGI:5446922
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mdm2^tm3.1Snj/Mdm2^tm3.1Snj	involves: 129S4/SvJae * C57BL/6	MGI:5446929

Genotype
MGI:5446929

hm1

• Allelic Composition: Mdm2^tm3.1Snj/Mdm2^tm3.1Snj
• Genetic Background: involves: 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased salivary gland tumor incidence ( J:189297 )

• in 24 months, 1 in 24 mice develops salivary gland epithelium

digestive/alimentary system

increased salivary gland tumor incidence ( J:189297 )

• in 24 months, 1 in 24 mice develops salivary gland epithelium

cellular

cellular phenotype ( J:189297 )

N • irradiated thymocytes exhibit normal apoptosis

N • untreated and irradiated mouse embryonic fibroblasts exhibit normal proliferation

endocrine/exocrine glands

increased salivary gland tumor incidence ( J:189297 )

• in 24 months, 1 in 24 mice develops salivary gland epithelium

immune system

immune system phenotype ( J:189297 )

N • irradiated thymocytes exhibit normal apoptosis

growth/size/body

increased salivary gland tumor incidence ( J:189297 )

• in 24 months, 1 in 24 mice develops salivary gland epithelium

craniofacial

increased salivary gland tumor incidence ( J:189297 )

• in 24 months, 1 in 24 mice develops salivary gland epithelium