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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gpr68tm1.1Aha
targeted mutation 1.1, Akihiro Harada
MGI:5445001
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gpr68tm1.1Aha/Gpr68tm1.1Aha B6.129(C)-Gpr68tm1.1Aha MGI:5445002


Genotype
MGI:5445002
hm1
Allelic
Composition		 Gpr68tm1.1Aha/Gpr68tm1.1Aha
Genetic
Background		 B6.129(C)-Gpr68tm1.1Aha
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gpr68tm1.1Aha mutation (0 available); any Gpr68 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased insulin secretion ( J:189192 )
• after glucose stimulation that is more severe in acidified islets
decreased circulating insulin level ( J:189192 )
• after glucose stimulation

endocrine/exocrine glands
endocrine/exocrine gland phenotype ( J:189192 )
N
• mice exhibit normal pancreatic islet morphology and physiology
decreased insulin secretion ( J:189192 )
• after glucose stimulation that is more severe in acidified islets




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory