All Phenotypes Ccr2<tm1.1Mpa> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ccr2^tm1.1Mpa
targeted mutation 1.1, Manolis Pasparakis
MGI:5444250

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ccr2^tm1.1Mpa/Ccr2^tm1.1Mpa	involves: BALB/cJ * C57BL/6	MGI:5444291

Allelic Composition	Ccr2^tm1.1Mpa/Ccr2^tm1.1Mpa
Genetic Background	involves: BALB/cJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr2^tm1.1Mpa mutation (0 available); any Ccr2 mutation (44 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

decreased macrophage cell number ( J:189044 )

• 7 days after skin wound injury

decreased monocyte cell number ( J:189044 )

• in unwounded mice

homeostasis/metabolism

abnormal wound healing ( J:189044 )

• 7 days after skin wound injury, mice exhibit reduced macrophage compared with control mice

• however, the rate of wound closure is normal

immune system

decreased macrophage cell number ( J:189044 )

• 7 days after skin wound injury

decreased monocyte cell number ( J:189044 )

• in unwounded mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24