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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hsp90aa1tm1.2Udon
targeted mutation 1.2, Heiichiro Udono
MGI:5441560
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ 		involves: C57BL/6 * C57BL/6NTac * FVB/N MGI:5441571


Genotype
MGI:5441571
cn1
Allelic
Composition		 Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon
Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic
Background		 involves: C57BL/6 * C57BL/6NTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm9(cre/ESR1)Arte mutation (2 available); any Gt(ROSA)26Sor mutation (942 available)
Hsp90aa1tm1.2Udon mutation (0 available); any Hsp90aa1 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
azoospermia ( J:187954 )
• in tamoxifen-treated mice
abnormal male germ cell apoptosis ( J:187954 )
• beyond the pachytene stage in tamoxifen-treated mice
small testis ( J:187954 )
• in tamoxifen-treated mice
decreased testis weight ( J:187954 )
• one third normal in tamoxifen-treated mice
testicular atrophy ( J:187954 )
• in tamoxifen-treated mice
arrest of spermatogenesis ( J:187954 )
• in tamoxifen-treated mice

cellular
azoospermia ( J:187954 )
• in tamoxifen-treated mice
abnormal male germ cell apoptosis ( J:187954 )
• beyond the pachytene stage in tamoxifen-treated mice

endocrine/exocrine glands
small testis ( J:187954 )
• in tamoxifen-treated mice
decreased testis weight ( J:187954 )
• one third normal in tamoxifen-treated mice
testicular atrophy ( J:187954 )
• in tamoxifen-treated mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory