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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ndrg2tm1Xzg
targeted mutation 1, Xizhi Guo
MGI:5441448
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ndrg2tm1Xzg/Ndrg2tm1Xzg
Tg(Col2a1-cre)1Bhr/0 		involves: 129S/SvEv * C57BL/6 * SJL MGI:5441473
cn2
 		Ndrg2tm1Xzg/Ndrg2tm1Xzg
Tg(Col1a1-cre)1Bek/0 		involves: 129S/SvEv * CD-1 MGI:5441472


Genotype
MGI:5441473
cn1
Allelic
Composition		 Ndrg2tm1Xzg/Ndrg2tm1Xzg
Tg(Col2a1-cre)1Bhr/0
Genetic
Background		 involves: 129S/SvEv * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndrg2tm1Xzg mutation (0 available); any Ndrg2 mutation (26 available)
Tg(Col2a1-cre)1Bhr mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal thoracic vertebrae morphology ( J:187603 )
• T9 is the transitional vertebra in 4 of 15 mice
thoracic vertebral transformation ( J:187603 )
• T13 to L1 transformation in 5 of 15 mice
lumbar vertebral transformation ( J:187603 )
• L6 to S1 transformation in 8 of 15 mice
sacral vertebral transformation ( J:187603 )
• S4 to S3 transformation in 6 of 15 mice




Genotype
MGI:5441472
cn2
Allelic
Composition		 Ndrg2tm1Xzg/Ndrg2tm1Xzg
Tg(Col1a1-cre)1Bek/0
Genetic
Background		 involves: 129S/SvEv * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ndrg2tm1Xzg mutation (0 available); any Ndrg2 mutation (26 available)
Tg(Col1a1-cre)1Bek mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
skeleton
abnormal thoracic vertebrae morphology ( J:187603 )
• T9 is the transitional vertebra in 4 of 16 mice
thoracic vertebral transformation ( J:187603 )
• T13 to L1 transformation in 7 of 16 mice
lumbar vertebral transformation ( J:187603 )
• L6 to S1 transformation in 14 of 16 mice
sacral vertebral transformation ( J:187603 )
• S4 to S3 transformation in 11 of 16 mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory