Analysis Tools|
Allele Symbol Allele Name Allele ID |
Tg(Igkv3-5*-MYC)#Plbe transgene insertion, P Leif Bergsagel MGI:5441311 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• median survival is 337 days
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• aggressive extramedullary monoclonal plasmacytoma with infiltration of spleen and lymph nodes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• unlike Tg(Igkv3-5*-Myc)#Plbe mice, no spikes in monoclonal antibodies (M-spikes) are observed
• mice exhibit fewer plasma cells in the bone marrow compared with Tg(Igkv3-5*-Myc)#Plbe mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 09/30/2025 MGI 6.24 |
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