All Phenotypes Tg(Myh6-Fhod3*I1127A)#Hsum MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Myh6-Fhod3*I1127A)#Hsum
transgene insertion, Hideki Sumimoto
MGI:5440647

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Fhod3^tm1Hsum/Fhod3⁺ Tg(Myh6-Fhod3*I1127A)#Hsum/0	involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj	MGI:5440665

Allelic Composition	Fhod3^tm1Hsum/Fhod3⁺ Tg(Myh6-Fhod3*I1127A)#Hsum/0
Genetic Background	involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fhod3^tm1Hsum mutation (0 available); any Fhod3 mutation (93 available)
Tg(Myh6-Fhod3*I1127A)#Hsum mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:187358 )

• all mice die by 3 weeks after birth

preweaning lethality, incomplete penetrance ( J:187358 )

• fewer than expected mice are present at P8

cardiovascular system

abnormal myocardium layer morphology ( J:187358 )

• at P7, ventricular walls lack the non-compact layer of myocardium

abnormal heart development ( J:187358 )

• premyofibrils fail to mature

thin ventricular wall ( J:187358 )

• at P7

dilated heart ( J:187358 )

• at P7

muscle

abnormal myocardium layer morphology ( J:187358 )

• at P7, ventricular walls lack the non-compact layer of myocardium

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24