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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nos3tm1.2Taka
targeted mutation 1.2, Takamune Takahashi
MGI:5438595
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nos3tm1.2Taka/Nos3tm1.2Taka involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA MGI:5438598


Genotype
MGI:5438598
hm1
Allelic
Composition		 Nos3tm1.2Taka/Nos3tm1.2Taka
Genetic
Background		 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos3tm1.2Taka mutation (0 available); any Nos3 mutation (56 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system

renal/urinary system
abnormal renal glomerulus morphology ( J:187860 )
• thrombotic glomerular lesions and focal renal scars containing crowded atubular glomeruli in most mice
• thrombotic/mesangiolytic glomeruli in some mice

homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory