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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hprt1tm2(CAG-Myof)Isrd
targeted mutation 2, Isabelle Richard
MGI:5438010
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hprt1tm2(CAG-Myof)Isrd/Hprt1tm2(CAG-Myof)Isrd involves: 129 * C57BL/6 MGI:5438017
cx2
 		Dysfprmd/Dysfprmd
Hprt1tm2(CAG-Myof)Isrd/Y 		involves: 129 * A/J * C57BL/6 MGI:5438018
cx3
 		Dysfprmd/Dysfprmd
Hprt1tm2(CAG-Myof)Isrd/Hprt1tm2(CAG-Myof)Isrd 		involves: 129 * A/J * C57BL/6 MGI:5438019
ot4
 		Hprt1tm2(CAG-Myof)Isrd/Y involves: 129 * C57BL/6 MGI:5438016


Genotype
MGI:5438017
hm1
Allelic
Composition		 Hprt1tm2(CAG-Myof)Isrd/Hprt1tm2(CAG-Myof)Isrd
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm2(CAG-Myof)Isrd mutation (0 available); any Hprt1 mutation (1274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
muscle phenotype ( J:187293 )
N
• muscles exhibit normal morphology and contractile function




Genotype
MGI:5438018
cx2
Allelic
Composition		 Dysfprmd/Dysfprmd
Hprt1tm2(CAG-Myof)Isrd/Y
Genetic
Background		 involves: 129 * A/J * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dysfprmd mutation (6 available); any Dysf mutation (183 available)
Hprt1tm2(CAG-Myof)Isrd mutation (0 available); any Hprt1 mutation (1274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
muscle phenotype ( J:187293 )
N
• after laser wounding, mice exhibit restored sarcolemmal repair in muscles
dystrophic muscle ( J:187293 )
• as in Dysfprmd homozygotes

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:187293 )
N
• after laser wounding, mice exhibit restored sarcolemmal repair in muscles




Genotype
MGI:5438019
cx3
Allelic
Composition		 Dysfprmd/Dysfprmd
Hprt1tm2(CAG-Myof)Isrd/Hprt1tm2(CAG-Myof)Isrd
Genetic
Background		 involves: 129 * A/J * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dysfprmd mutation (6 available); any Dysf mutation (183 available)
Hprt1tm2(CAG-Myof)Isrd mutation (0 available); any Hprt1 mutation (1274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:187293 )
N
• after laser wounding, mice exhibit restored sarcolemmal repair in muscles

muscle
muscle phenotype ( J:187293 )
N
• after laser wounding, mice exhibit restored sarcolemmal repair in muscles
dystrophic muscle ( J:187293 )
• as in Dysfprmd homozygotes




Genotype
MGI:5438016
ot4
Allelic
Composition		 Hprt1tm2(CAG-Myof)Isrd/Y
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm2(CAG-Myof)Isrd mutation (0 available); any Hprt1 mutation (1274 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
muscle phenotype ( J:187293 )
N
• muscles exhibit normal morphology and contractile function




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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory