Phenotypes associated with this allele

• Allele Symbol: Elmod1^rda-2J
• Allele Name: roundabout 2 Jackson
• Allele ID: MGI:5437446
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Elmod1^rda-2J/Elmod1^rda-2J	B6.Cg-Elmod1^rda-2J/JKjn	MGI:5437998
ht2	Elmod1^rda-2J/Elmod1^+	B6.Cg-Elmod1^rda-2J/JKjn	MGI:5883633

Genotype
MGI:5437998

hm1

• Allelic Composition: Elmod1^rda-2J/Elmod1^rda-2J
• Genetic Background: B6.Cg-Elmod1^rda-2J/JKjn

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Cochlear hair cell abnormalities in rda/rda and Elmod1^rda-2J/Elmod1^rda-2J mice

hearing/vestibular/ear

abnormal cochlear hair cell stereociliary bundle morphology ( J:187273 )

organ of Corti degeneration ( J:187273 )

• at 4 months

increased or absent threshold for auditory brainstem response ( J:187273 )

deafness ( J:187273 )

• profound by 5 weeks

behavior/neurological

absent startle reflex ( J:187273 )

circling ( J:187273 )

nervous system

abnormal cochlear hair cell stereociliary bundle morphology ( J:187273 )

cochlear ganglion degeneration ( J:187273 )

• at 4 months

Genotype
MGI:5883633

ht2

• Allelic Composition: Elmod1^rda-2J/Elmod1⁺
• Genetic Background: B6.Cg-Elmod1^rda-2J/JKjn

hearing/vestibular/ear

hearing/vestibular/ear phenotype ( J:187273 )

N • heterozygotes have normal hearing