About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Scgb1a1tm1(icre)Fjd
targeted mutation 1, Franco J DeMayo
MGI:5433101
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Foxp1tm1.1Pwt/Foxp1tm1.1Pwt
Foxp4tm2.1Eem/Foxp4tm2.1Eem
Scgb1a1tm1(icre)Fjd/Scgb1a1+ 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:5433107


Genotype
MGI:5433107
cn1
Allelic
Composition		 Foxp1tm1.1Pwt/Foxp1tm1.1Pwt
Foxp4tm2.1Eem/Foxp4tm2.1Eem
Scgb1a1tm1(icre)Fjd/Scgb1a1+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp1tm1.1Pwt mutation (1 available); any Foxp1 mutation (75 available)
Foxp4tm2.1Eem mutation (0 available); any Foxp4 mutation (91 available)
Scgb1a1tm1(icre)Fjd mutation (1 available); any Scgb1a1 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
respiratory system
abnormal respiratory system development ( J:185603 )
• mice exhibit an increase in goblet cell differentiation compared with control mice
abnormal respiratory system physiology ( J:185603 )
• following naphthalene injury, mice exhibit defective epithelial regeneration by ectopically activating goblet cell fate compared with control mice

homeostasis/metabolism
increased susceptibility to injury ( J:185603 )
• following naphthalene injury, mice exhibit defective epithelial regeneration by ectopically activating goblet cell fate compared with control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory