Phenotypes associated with this allele

• Allele Symbol: Rock2^{Gt(OST440776)Lex}
• Allele Name: gene trap OST440776, Lexicon Genomics
• Allele ID: MGI:5431873
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rock2^Gt(OST440776)Lex/Rock2^Gt(OST440776)Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:5431104

Genotype
MGI:5431104

hm1

• Allelic Composition: Rock2^{Gt(OST440776)Lex}/Rock2^{Gt(OST440776)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:186058 )

• fewer than expected mice are produced from heterozygote crosses

vision/eye

retina neovascularization ( J:186058 )

• in 2 of 17 mice

decreased eye anterior chamber depth ( J:186058 )

• extremely shallow anterior chamber in 7 of 17 mice

retina degeneration ( J:186058 )

• on inner retina in 1 of 17 mice

ocular hypotension ( J:186058 )

growth/size/body

decreased body size ( J:186058 )

decreased body weight ( J:186058 )

cardiovascular system

retina neovascularization ( J:186058 )

• in 2 of 17 mice