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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tnfsf15tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:5431588
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Tnfsf15tm1Lex/Tnfsf15tm1Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:5431590


Genotype
MGI:5431590
hm1
Allelic
Composition		 Tnfsf15tm1Lex/Tnfsf15tm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfsf15tm1Lex mutation (2 available); any Tnfsf15 mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased NK cell number ( J:82809 )
• homozygous mutant mice exhibit an increased mean percentage of natural killer cells in peripheral blood when compared to controls

immune system
increased NK cell number ( J:82809 )
• homozygous mutant mice exhibit an increased mean percentage of natural killer cells in peripheral blood when compared to controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory