All Phenotypes Notch1<tm2.1Rko> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Notch1^tm2.1Rko
targeted mutation 2.1, Raphael Kopan
MGI:5431503

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Notch1^tm2.1Rko/Notch1⁺	Not Specified	MGI:5431506

Allelic Composition	Notch1^tm2.1Rko/Notch1⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Notch1^tm2.1Rko mutation (0 available); any Notch1 mutation (115 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal vertebrae morphology ( J:186213 )

• increased rate and severity of vertebrae defects after mild hypoxia, predominantly in the caudal thorax to lumbar region

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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