All Phenotypes Rock1<tm1Lex> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Rock1^tm1Lex
targeted mutation 1, Lexicon Genomics
MGI:5431098

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Rock1^tm1Lex/Rock1^tm1Lex	involves: 129S5/SvEvBrd * C57BL/6J	MGI:5431103

Allelic Composition	Rock1^tm1Lex/Rock1^tm1Lex
Genetic Background	involves: 129S5/SvEvBrd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rock1^tm1Lex mutation (1 available); any Rock1 mutation (57 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

lethality, incomplete penetrance ( J:186058 )

• fewer than expected mice are produced from heterozygote crosses

premature death ( J:186058 )

• some mice die before 1 month of age

vision/eye

vision/eye phenotype ( J:186058 )

N	• surviving mice exhibit normal ocular surface anatomy

ocular hypotension ( J:186058 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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