About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu
targeted mutation 1, Xiao-Hong Sun
MGI:5430379
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu/Gt(ROSA)26Sor+
Tg(Lck-cre)548Jxm/0 		B6.Cg-Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu Tg(Lck-cre)548Jxm MGI:5432021


Genotype
MGI:5432021
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu/Gt(ROSA)26Sor+
Tg(Lck-cre)548Jxm/0
Genetic
Background		 B6.Cg-Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu Tg(Lck-cre)548Jxm
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(NOTCH1/GFP)Xhsu mutation (0 available); any Gt(ROSA)26Sor mutation (1046 available)
Tg(Lck-cre)548Jxm mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:185287 )
• median survival of 10 weeks

neoplasm
increased T cell derived lymphoma incidence ( J:185287 )
• large tumors with metastasis to lymph nodes, livers and/or kidney

endocrine/exocrine glands
increased T cell derived lymphoma incidence ( J:185287 )
• large tumors with metastasis to lymph nodes, livers and/or kidney

immune system
increased T cell derived lymphoma incidence ( J:185287 )
• large tumors with metastasis to lymph nodes, livers and/or kidney

hematopoietic system
increased T cell derived lymphoma incidence ( J:185287 )
• large tumors with metastasis to lymph nodes, livers and/or kidney




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory