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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gja1tm5Gfi
targeted mutation 5, Glenn I Fishman
MGI:5430316
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Gja1tm5Gfi/Gja1tm5Gfi involves: 129S1/Sv * 129X1/SvJ * CD-1 MGI:5430319


Genotype
MGI:5430319
hm1
Allelic
Composition		 Gja1tm5Gfi/Gja1tm5Gfi
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gja1tm5Gfi mutation (0 available); any Gja1 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:185692 )
N
• significantly diminished conduction velocities after transverse aortic constriction as in controls
• electrical induction of tachycardia occurs as in controls
abnormal cardiac muscle contractility ( J:185692 )
• significantly increased action potential duration after transverse aortic constriction, unlike controls

muscle
abnormal cardiac muscle contractility ( J:185692 )
• significantly increased action potential duration after transverse aortic constriction, unlike controls




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory