Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arap3tm1.1Sve mutation
(0 available);
any
Arap3 mutation
(61 available)
Arap3tm1.2Sve mutation
(0 available);
any
Arap3 mutation
(61 available)
Edil3Tg(Sox2-cre)1Amc mutation
(5 available);
any
Edil3 mutation
(42 available)
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mortality/aging
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• die around E11
• identical to mice homozygous for Arap3tm1.2Sve
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embryo
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• identical to mice homozygous for Arap3tm1.2Sve
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• defect in labyrinth formation
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cardiovascular system
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• identical to mice homozygous for Arap3tm1.2Sve
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growth/size/body
integument
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arap3tm1.1Sve mutation
(0 available);
any
Arap3 mutation
(61 available)
Arap3tm1.2Sve mutation
(0 available);
any
Arap3 mutation
(61 available)
Tg(Tek-cre)1Ywa mutation
(6 available)
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mortality/aging
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• die around E11
• identical to mice homozygous for Arap3tm1.2Sve
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cardiovascular system
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• the capillary network is replaced with a large accumulation of endothelial cells
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• identical to mice homozygous for Arap3tm1.2Sve
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• defect in vascular maturation and remodeling, especially apparent in the midbrain
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• unevenly sized vessel lumens, some of which are large, giving an impression of accumulations of endothelial cells
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embryo
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• identical to mice homozygous for Arap3tm1.2Sve
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• unevenly sized vessel lumens, some of which are large, giving an impression of accumulations of endothelial cells
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• defect in labyrinth formation
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• identical to mice homozygous for Arap3tm1.2Sve
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• wrinkled yolk sac at E10.5
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• the primary vascular plexus fails to remodel
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growth/size/body
integument
nervous system
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• the capillary network is replaced with a large accumulation of endothelial cells
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