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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Preptm1Dgen
targeted mutation 1, Deltagen
MGI:5427690
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Preptm1Dgen/Preptm1Dgen involves: 129P2/OlaHsd * C57BL/6J MGI:5427853


Genotype
MGI:5427853
hm1
Allelic
Composition		 Preptm1Dgen/Preptm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Preptm1Dgen mutation (2 available); any Prep mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
increased startle reflex ( J:82809 )
• homozygous mutant mice exhibited significantly increased startle responses

nervous system
decreased prepulse inhibition ( J:82809 )
• decreased prepulse inhibition when compared with age- and sex-matched wild-type control mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory