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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Adgrl2tm1Dgen
targeted mutation 1, Deltagen
MGI:5427677
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Adgrl2tm1Dgen/Adgrl2tm1Dgen involves: 129P2/OlaHsd * C57BL/6J MGI:5427831
ht2
 		Adgrl2tm1Dgen/Adgrl2+ involves: 129P2/OlaHsd * C57BL/6J MGI:5427832


Genotype
MGI:5427831
hm1
Allelic
Composition		 Adgrl2tm1Dgen/Adgrl2tm1Dgen
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrl2tm1Dgen mutation (2 available); any Adgrl2 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, complete penetrance ( J:82809 )
• homozygous mutant embryos die at approximately E15.5




Genotype
MGI:5427832
ht2
Allelic
Composition		 Adgrl2tm1Dgen/Adgrl2+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrl2tm1Dgen mutation (2 available); any Adgrl2 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
decreased locomotor activity ( J:82809 )
• heterozygous mutant mice exhibited significantly decreased total distance traveled during open field testing when compared with age- and sex-matched wild-type control mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory