All Phenotypes Adamts1<tm1Dgen> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Adamts1^tm1Dgen
targeted mutation 1, Deltagen
MGI:5427602

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Adamts1^tm1Dgen/Adamts1^tm1Dgen	involves: 129P2/OlaHsd * C57BL/6J	MGI:5427736

Allelic Composition	Adamts1^tm1Dgen/Adamts1^tm1Dgen
Genetic Background	involves: 129P2/OlaHsd * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts1^tm1Dgen mutation (2 available); any Adamts1 mutation (64 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

abnormal kidney morphology ( J:82809 )

• discolored, 49 day homozygous mutant male

enlarged kidney ( J:82809 )

• enlarged and fluid-filled, 49 day homozygous mutant females and males

increased kidney weight ( J:82809 )

• weight and/or organ weight/body weight ratio increased, 49 day homozygous mutant females and males

kidney cortex atrophy ( J:82809 )

• cortex atrophic, 49 day homozygous females and males

hydronephrosis ( J:82809 )

• pelvis dilated, bilateral, 49 day homozygous females and males; unilateral, 49 day homozygous female

growth/size/body

enlarged kidney ( J:82809 )

• enlarged and fluid-filled, 49 day homozygous mutant females and males

increased kidney weight ( J:82809 )

• weight and/or organ weight/body weight ratio increased, 49 day homozygous mutant females and males

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