Phenotypes associated with this allele

• Allele Symbol: Tg(Fabp4-Fcor)1Jnak
• Allele Name: transgene insertion 1, Jun Nakae
• Allele ID: MGI:5427594
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Lepr^db/Lepr^db Tg(Fabp4-Fcor)1Jnak/0	involves: C57BL/6 * C57BLKS/J * DBA/2	MGI:5427610
tg2	Tg(Fabp4-Fcor)1Jnak/0	involves: C57BL/6 * DBA/2	MGI:5427608

Genotype
MGI:5427610

cx1

• Allelic Composition: Lepr^db/Lepr^db; Tg(Fabp4-Fcor)1Jnak/0
• Genetic Background: involves: C57BL/6 * C57BLKS/J * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased oxygen consumption ( J:184684 )

• compared with Lepr^db homozygotes

improved glucose tolerance ( J:184684 )

• compared with Lepr^db homozygotes

increased insulin sensitivity ( J:184684 )

• compared with Lepr^db homozygotes

adipose tissue

decreased abdominal adipose tissue amount ( J:184684 )

• decreased visceral fat compared with Lepr^db homozygotes

• however, subcutaneous and total adipose mass are normal

decreased white fat cell size ( J:184684 )

• compared with Lepr^db homozygotes

growth/size/body

decreased body weight ( J:184684 )

• compared with Lepr^db homozygotes

Genotype
MGI:5427608

tg2

• Allelic Composition: Tg(Fabp4-Fcor)1Jnak/0
• Genetic Background: involves: C57BL/6 * DBA/2

adipose tissue

decreased subcutaneous adipose tissue amount ( J:184684 )

decreased white adipose tissue amount ( J:184684 )

• of visceral and subcutaneous depots at 24 weeks but not 12 weeks

decreased total body fat amount ( J:184684 )

decreased white fat cell size ( J:184684 )

homeostasis/metabolism

decreased respiratory quotient ( J:184684 )

increased insulin sensitivity ( J:184684 )

• at 4 months

growth/size/body

weight loss ( J:184684 )

• adult-onset

integument

decreased subcutaneous adipose tissue amount ( J:184684 )