Phenotypes associated with this allele

• Allele Symbol: Pbx1^tm1.2Koss
• Allele Name: targeted mutation 1.2, Matthew J Koss
• Allele ID: MGI:5426975
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Pbx1^tm1.1Koss/Pbx1^tm1.2Koss Tmem163^Tg(ACTB-cre)2Mrt/0	involves: 129P2/OlaHsd * FVB/N	MGI:5426978

Genotype
MGI:5426978

cn1

• Allelic Composition: Pbx1^tm1.1Koss/Pbx1^tm1.2Koss; Tmem163^{Tg(ACTB-cre)2Mrt}/0
• Genetic Background: involves: 129P2/OlaHsd * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

absent spleen ( J:184521 )

skeleton

abnormal humerus morphology ( J:184521 )

• phenotype duplicates that of global null mice

• fusion of the glenoid cavity of the scapula to the humeral head

• partial duplication of the head

abnormal deltoid tuberosity morphology ( J:184521 )

• detached

abnormal scapula morphology ( J:184521 )

• fusion of the glenoid cavity to the humeral head

scapular bone hypoplasia ( J:184521 )

• thin and hypoplastic

abnormal rib morphology ( J:184521 )

• phenotype duplicates that of global null mice

• truncated, dysmorphic, and occasionally fused ribs

rib fusion ( J:184521 )

• occasional

short ribs ( J:184521 )

• truncated

immune system

absent spleen ( J:184521 )

limbs/digits/tail

abnormal humerus morphology ( J:184521 )

• phenotype duplicates that of global null mice

• fusion of the glenoid cavity of the scapula to the humeral head

• partial duplication of the head

abnormal deltoid tuberosity morphology ( J:184521 )

• detached