Phenotypes associated with this allele

• Allele Symbol: Il15^m1Hwata
• Allele Name: mutation 1, Hiroshi Watarai
• Allele ID: MGI:5426268
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Il15^m1Hwata/Il15^m1Hwata	Not Specified	MGI:5426351

Genotype
MGI:5426351

hm1

• Allelic Composition: Il15^m1Hwata/Il15^m1Hwata
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased NK cell number ( J:184570 )

• in the spleen and in the liver

abnormal NK T cell number ( J:184570 )

• more than 4 times increase in the percentage of IL17RB+ invariant NK T cells

decreased NK T cell number ( J:184570 )

• in invariant NK T cells in the spleen, liver and thymus

decreased interferon-gamma secretion ( J:184570 )

• in invariant NK T cells co-cultured with GM-CSF-induced bone marrow derived dendritic cells treated with alpha-GalCer

• in invariant NK T cells stimulated with alpha-GalCer

abnormal interleukin secretion ( J:184570 )

• invariant NK T cells co-cultured with bone marrow-derived dendritic cells from Cd1d1^tm1Luc homozygotes fail to secrete any interleukins

hematopoietic system

decreased NK cell number ( J:184570 )

• in the spleen and in the liver

abnormal NK T cell number ( J:184570 )

• more than 4 times increase in the percentage of IL17RB+ invariant NK T cells

decreased NK T cell number ( J:184570 )

• in invariant NK T cells in the spleen, liver and thymus