All Phenotypes Hes7<tm3.1Dihz> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Hes7^tm3.1Dihz
targeted mutation 3.1, David Ish-Horowicz
MGI:5426215

Summary

2 genotypes

Allelic Composition	Hes7^tm3.1Dihz/Hes7^tm3.1Dihz
Genetic Background	involves: 129 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hes7^tm3.1Dihz mutation (0 available); any Hes7 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

• mice die between birth and weaning

skeleton

abnormal skeleton morphology ( J:184024 )

abnormal rib morphology ( J:184024 )

• extensive and severe malformations at E18.5

rib fusion ( J:184024 )

• at E18.5

abnormal vertebrae morphology ( J:184024 )

• extensive and severe malformations at E18.5

• at E18.5

vertebral fusion ( J:184024 )

• at E18.5

embryo

abnormal somite development ( J:184024 )

• mice exhibit disorganized expression of the segmentation marker Uncx4.1

limbs/digits/tail

short tail ( J:184024 )

• at E18.5

Allelic Composition	Hes7^tm3.1Dihz/Hes7⁺
Genetic Background	involves: 129 * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hes7^tm3.1Dihz mutation (0 available); any Hes7 mutation (24 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

kinked tail ( J:184024 )

• in few mice

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