About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mir21atm1.1Sho
targeted mutation 1.1, Stuart H Orkin
MGI:5319685
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mir21atm1.1Sho/Mir21atm1.1Sho involves: 129 * C57BL/6 MGI:5319691


Genotype
MGI:5319691
hm1
Allelic
Composition		 Mir21atm1.1Sho/Mir21atm1.1Sho
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir21atm1.1Sho mutation (0 available); any Mir21a mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
decreased susceptibility to kidney reperfusion injury ( J:183786 )
• decrease in interstitial fibrosis, apoptosis, and tubule injury scores following either unilateral ureteral obstruction or unilateral ischemia reperfusion injury

homeostasis/metabolism
decreased susceptibility to kidney reperfusion injury ( J:183786 )
• decrease in interstitial fibrosis, apoptosis, and tubule injury scores following either unilateral ureteral obstruction or unilateral ischemia reperfusion injury




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory