About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Ago1tm1.1Tara
targeted mutation 1.1, Alexander Tarakhovsky
MGI:5319524
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Ago1tm1.1Tara/Ago1tm1.1Tara
Ago2tm1.1Tara/Ago2tm1.1Tara
Tg(KRT14-cre)1Efu/0
involves: 129P2/OlaHsd MGI:5319527
cn2
Ago1tm1.1Tara/Ago1tm1.1Tara
Tg(KRT14-cre)1Efu/0
Not Specified MGI:5319526


Genotype
MGI:5319527
cn1
Allelic
Composition
Ago1tm1.1Tara/Ago1tm1.1Tara
Ago2tm1.1Tara/Ago2tm1.1Tara
Tg(KRT14-cre)1Efu/0
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ago1tm1.1Tara mutation (1 available); any Ago1 mutation (156 available)
Ago2tm1.1Tara mutation (1 available); any Ago2 mutation (54 available)
Tg(KRT14-cre)1Efu mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• evaginating hair follicle cysts in the epidermis at P4
• evaginating hair follicle cysts in the epidermis at P4
• shortened and misangled hair follicle growth at P4
• hyperthickened
• apoptotic cells in the basal epidermis

growth/size/body
• evaginating hair follicle cysts in the epidermis at P4




Genotype
MGI:5319526
cn2
Allelic
Composition
Ago1tm1.1Tara/Ago1tm1.1Tara
Tg(KRT14-cre)1Efu/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ago1tm1.1Tara mutation (1 available); any Ago1 mutation (156 available)
Tg(KRT14-cre)1Efu mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• no developmental defects are detected





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory