About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Rhdtm1Goo
targeted mutation 1, Dominique Goossens
MGI:5318588
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Rhdtm1Goo/Rhdtm1Goo involves: 129P2/OlaHsd * C57BL/6 MGI:5318590
cx2
 		Rhagtm1Goo/Rhagtm1Goo
Rhdtm1Goo/Rhdtm1Goo 		involves: 129P2/OlaHsd * C57BL/6 MGI:5318591


Genotype
MGI:5318590
hm1
Allelic
Composition		 Rhdtm1Goo/Rhdtm1Goo
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhdtm1Goo mutation (2 available); any Rhd mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal erythrocyte physiology ( J:182122 )
• the alkalinisation rate constant values for ghosts are reduced by 30-40% compared to wild-type red blood cells
• basal adhesion to bEnd.3 endothelial cells is reduced

homeostasis/metabolism
increased circulating iron level ( J:182122 )
• slightly increased at 17 weeks of age




Genotype
MGI:5318591
cx2
Allelic
Composition		 Rhagtm1Goo/Rhagtm1Goo
Rhdtm1Goo/Rhdtm1Goo
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhagtm1Goo mutation (2 available); any Rhag mutation (29 available)
Rhdtm1Goo mutation (2 available); any Rhd mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:182122 )
N
• not anaemic and show no obvious anomalies in standard haematological parameters or in erythrocyte morphology or fragility

homeostasis/metabolism
homeostasis/metabolism phenotype ( J:182122 )
N
• no significant changes in iron, transferrin, or ferritin levels

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT Rh deficiency syndrome DOID:0050641 OMIM:268150
 J:182122




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory