Phenotypes associated with this allele

• Allele Symbol: Cdk1^tm2.2Kald
• Allele Name: targeted mutation 2.2, Philipp Kaldis
• Allele ID: MGI:5318086
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cdk1^tm2.2Kald/Cdk1^tm2.2Kald	involves: 129 * C57BL/6 * FVB/N * SJL	MGI:5318111

Genotype
MGI:5318111

hm1

• Allelic Composition: Cdk1^tm2.2Kald/Cdk1^tm2.2Kald
• Genetic Background: involves: 129 * C57BL/6 * FVB/N * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:182141 )

• mice die between E3.5 and E10.5

embryo

failure of zygotic cell division ( J:182141 )

• after maternal mRNA runs out

abnormal blastocyst morphology ( J:182141 )

• blastocysts exhibit decreased number of enlarged nuclei compared with wild-type blastocysts

cellular

abnormal cell nucleus morphology ( J:182141 )

• blastocysts exhibit decreased number of enlarged nuclei compared with wild-type blastocysts

abnormal cell nucleus count ( J:182141 )

• decreased number in blastocysts