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Allele Symbol Allele Name Allele ID |
Tg(Col11a2-SIK3)#Ntsu transgene insertion, Noriyuki Tsumaki MGI:5317919 |
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| Summary |
2 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• nearly all mice die on the first day after birth
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| N |
• the impaired chondrocyte hypertrophy phenotype observed in Sik3tm1Ntsu homozygotes is rescued at E16.5 and E18.5
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the growth plate in the hind limb of aging mice disappears unlike in wild-type mice
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• at 6 months of age
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• disappears by 8 weeks of age
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/21/2024 MGI 6.23 |
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