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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Mir34a+
wild type
MGI:5317671
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Mir34atm1.2Arte/Mir34a+
Tg(Neurod2-Smo*A1)199Jols/0
involves: C57BL/6 * C57BL/6N MGI:5791915


Genotype
MGI:5791915
cx1
Allelic
Composition
Mir34atm1.2Arte/Mir34a+
Tg(Neurod2-Smo*A1)199Jols/0
Genetic
Background
involves: C57BL/6 * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir34atm1.2Arte mutation (0 available); any Mir34a mutation (12 available)
Tg(Neurod2-Smo*A1)199Jols mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• 75% medulloblastoma incidence
• mice show increased medulloblastoma incidence and time to tumor formation compared to single Tg(Neurod2-Smo*A1)199Jols hemizygotes

nervous system
• 75% medulloblastoma incidence
• mice show increased medulloblastoma incidence and time to tumor formation compared to single Tg(Neurod2-Smo*A1)199Jols hemizygotes





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory