All Phenotypes Gjc1<tm1.2(Gjd2)Kwi> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Gjc1^{tm1.2(Gjd2)Kwi}
targeted mutation 1.2, Klaus Willecke
MGI:5317163

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Gjc1^{tm1.2(Gjd2)Kwi}/Gjc1^{tm1.2(Gjd2)Kwi}	involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL	MGI:5317175

Allelic Composition	Gjc1^{tm1.2(Gjd2)Kwi}/Gjc1^{tm1.2(Gjd2)Kwi}
Genetic Background	involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gjc1^{tm1.2(Gjd2)Kwi} mutation (0 available); any Gjc1 mutation (35 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:182927 )

• at E11.5

cardiovascular system

enlarged heart ( J:182927 )

decreased cardiac muscle contractility ( J:182927 )

• the heart contracts weakly until E11.5

embryo

embryonic growth retardation ( J:182927 )

• at E10.5 and E11.5

decreased embryo size ( J:182927 )

• at E10.5 and E11.5

growth/size/body

enlarged heart ( J:182927 )

embryonic growth retardation ( J:182927 )

• at E10.5 and E11.5

decreased embryo size ( J:182927 )

• at E10.5 and E11.5

muscle

decreased cardiac muscle contractility ( J:182927 )

• the heart contracts weakly until E11.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 09/30/2025 MGI 6.24