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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Six1tm1Px
targeted mutation 1, Pin-Xian Xu
MGI:5316866
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Six1tm1Px/Six1tm1Px
Tg(Atoh1-cre/Esr1*)14Fsh/0 		involves: FVB/N MGI:5316868


Genotype
MGI:5316868
cn1
Allelic
Composition		 Six1tm1Px/Six1tm1Px
Tg(Atoh1-cre/Esr1*)14Fsh/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Six1tm1Px mutation (0 available); any Six1 mutation (19 available)
Tg(Atoh1-cre/Esr1*)14Fsh mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal cochlear hair cell morphology ( J:181471 )
• authors state that tamoxifen-treated mice exhibit the same phenotype as in Eya1tm2Px/Eya1tm2Px Tg(Atoh1-cre/Esr1*)14Fsh mice

nervous system
abnormal cochlear hair cell morphology ( J:181471 )
• authors state that tamoxifen-treated mice exhibit the same phenotype as in Eya1tm2Px/Eya1tm2Px Tg(Atoh1-cre/Esr1*)14Fsh mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory