Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ror1tm1.2Meg mutation
(0 available);
any
Ror1 mutation
(57 available)
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Rare exencephaly in Ror1tm1.2Meg/Ror1tm1.2Meg mice
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ror1tm1.2Meg mutation
(0 available);
any
Ror1 mutation
(57 available)
Ror2tm1.2Meg mutation
(0 available);
any
Ror2 mutation
(123 available)
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Ror1tm1.2Meg/Ror1tm1.2Meg Ror2tm1.2Meg/Ror2tm1.2Meg embryos exhibit morphogenesis defects
mortality/aging
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• do not survive to term and most die by E15.5
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craniofacial
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• more severe facial malformations than in Ror2tm1.2Meg single homozygotes
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limbs/digits/tail
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• more severe truncation of the limbs than in Ror2tm1.2Meg single homozygotes
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embryo
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• more severe than in Ror2tm1.2Meg single homozygotes
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homeostasis/metabolism
nervous system
growth/size/body
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• more severe facial malformations than in Ror2tm1.2Meg single homozygotes
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