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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mir137tm1Mtm
targeted mutation 1, Michael McManus
MGI:5314770
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mir137tm1Mtm/Mir137tm1Mtm involves: 129P2/OlaHsd * C57BL/6J MGI:6118112
ht2
 		Mir137tm1Mtm/Mir137+ involves: 129P2/OlaHsd * C57BL/6J MGI:6118117


Genotype
MGI:6118112
hm1
Allelic
Composition		 Mir137tm1Mtm/Mir137tm1Mtm
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir137tm1Mtm mutation (1 available); any Mir137 mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:244465 )
• embryos die between E4.5 and E11.5
• no embryos found at E11.5
• increased number of resorbed embryos




Genotype
MGI:6118117
ht2
Allelic
Composition		 Mir137tm1Mtm/Mir137+
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir137tm1Mtm mutation (1 available); any Mir137 mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:244465 )
N
• normal behavior in open field, elevated plus maze, rotarod, Morris water maze, hot plate, sociability and social novelty, acoustic startle responses, and marble-burying tests

mortality/aging
mortality/aging ( J:244465 )
N
• viable




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory