All Phenotypes Mavs<tm1Itl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mavs^tm1Itl
targeted mutation 1, inGenious Targeting Laboratory
MGI:5313532

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Mavs^tm1Itl/Mavs^tm1Itl Trex1^tm1Tld/Trex1^tm1Tld	involves: 129P2/OlaHsd * C57BL/6	MGI:5317329

Allelic Composition	Mavs^tm1Itl/Mavs^tm1Itl Trex1^tm1Tld/Trex1^tm1Tld
Genetic Background	involves: 129P2/OlaHsd * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mavs^tm1Itl mutation (0 available); any Mavs mutation (36 available)
Trex1^tm1Tld mutation (2 available); any Trex1 mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:181257 )

• as in Trex1^tm1Tld homozygotes

immune system

increased inflammatory response ( J:181257 )

• in the skeletal muscle, tongue, skin, glandular stomach and heart as in Trex1^tm1Tld homozygotes

myocarditis ( J:181257 )

stomach inflammation ( J:181257 )

myositis ( J:181257 )

skin inflammation ( J:181257 )

cardiovascular system

myocarditis ( J:181257 )

digestive/alimentary system

stomach inflammation ( J:181257 )

integument

skin inflammation ( J:181257 )

muscle

myositis ( J:181257 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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