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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Vldlrtm1Lex
targeted mutation 1, Lexicon Genetics
MGI:5312686
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Vldlrtm1Lex/Vldlrtm1Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:5312692


Genotype
MGI:5312692
hm1
Allelic
Composition		 Vldlrtm1Lex/Vldlrtm1Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vldlrtm1Lex mutation (1 available); any Vldlr mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
retina neovascularization ( J:181399 )
• however, injection of an anti-FZD4 antibodies decreases retinal neovascularization
• as early as P14
increased vascular permeability ( J:181399 )
• when treated with anti-FZD4 antibodies

vision/eye
retina neovascularization ( J:181399 )
• as early as P14
• however, injection of an anti-FZD4 antibodies decreases retinal neovascularization




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory