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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tnfrsf21tm2Gne
targeted mutation 2, Genentech
MGI:5312063
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Tnfrsf21tm2Gne/Tnfrsf21tm2Gne
Tg(Tek-cre)1Ywa/0 		involves: C57BL/6 * SJL MGI:5312098


Genotype
MGI:5312098
cn1
Allelic
Composition		 Tnfrsf21tm2Gne/Tnfrsf21tm2Gne
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tek-cre)1Ywa mutation (7 available)
Tnfrsf21tm2Gne mutation (0 available); any Tnfrsf21 mutation (63 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal brain vasculature morphology ( J:181470 )
• embryonic hindbrain radial vessel density is significantly reduced
intracranial hemorrhage ( J:181470 )
• forebrain specific hemorrhages during development

nervous system
abnormal brain vasculature morphology ( J:181470 )
• embryonic hindbrain radial vessel density is significantly reduced
intracranial hemorrhage ( J:181470 )
• forebrain specific hemorrhages during development




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory